Noninvasive measurement of systemic vascular resistance using Doppler echocardiography

Amr E. Abbas, F. David Fortuin, Bhavesh Patel, Carlos A. Moreno, Nelson B. Schiller, Steven J. Lester

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Background Systemic vascular resistance (SVR) is an integral therapeutic component of patients with heart failure and shock. We hypothesized that the ratio of the peak mitral regurgitant velocity (MRV) (m/s) to left ventricular outflow time-velocity integral (TVILVOT) (cm) by Doppler would provide a noninvasive correlate of SVR. Methods SVR was correlated to MRV/TVILVOT in 33 patients undergoing right heart catheterization. Receiver operating characteristic curves were generated to determine the best-balanced sensitivity and specificity to identify SVR > 14 Wood units (WU) and <10 WU. Results MRV/TVILVOT correlated well with SVR (r = 0.842, 95% confidence interval 0.7-0.92, P < .001, Y = 0.459 + 49.397*X). By receiver operating characteristics, MRV/TVILVOT > 0.27 had a 70% sensitivity and a 77% specificity to identify SVR > 14 WU. MRV/TVILVOT < 0.2 had a 92% sensitivity and a 88% specificity to identify SVR < 10 WU. Conclusion Doppler echocardiography provides a reliable noninvasive assessment of SVR.

Original languageEnglish (US)
Pages (from-to)834-838
Number of pages5
JournalJournal of the American Society of Echocardiography
Issue number8
StatePublished - Aug 2004

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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