No association of germline alteration of MSR1 with prostate cancer risk

Liang Wang; Shannon K. McDonnell; Julie M. Cunningham; Scott Hebbring; Steven J. Jacobsen; James R. Cerhan; Susan L. Slager; Michael L. Blute; Daniel J. Schaid; Stephen N. Thibodeau

doi:10.1038/ng1239

No association of germline alteration of MSR1 with prostate cancer risk

Liang Wang
, Shannon K. McDonnell
, Julie M. Cunningham
, Scott Hebbring
, Steven J. Jacobsen
, James R. Cerhan
, Susan L. Slager
, Michael L. Blute
, Daniel J. Schaid
, Stephen N. Thibodeau

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

The macrophage scavenger receptor 1 gene (MSR1) was recently identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer. To confirm these findings, we screened MSR1 for germline mutations among individuals with familial prostate cancer and tested gene variants for associations in both sporadic and familial prostate cancer. Our results do not support MSR1 as a risk factor for prostate cancer.

Original language	English (US)
Pages (from-to)	128-129
Number of pages	2
Journal	Nature Genetics
Volume	35
Issue number	2
DOIs	https://doi.org/10.1038/ng1239
State	Published - Oct 1 2003

ASJC Scopus subject areas

Genetics

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10.1038/ng1239

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@article{a56f8d71972a4fe5bacdfa628c74dcc4,

title = "No association of germline alteration of MSR1 with prostate cancer risk",

abstract = "The macrophage scavenger receptor 1 gene (MSR1) was recently identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer. To confirm these findings, we screened MSR1 for germline mutations among individuals with familial prostate cancer and tested gene variants for associations in both sporadic and familial prostate cancer. Our results do not support MSR1 as a risk factor for prostate cancer.",

author = "Liang Wang and McDonnell, \{Shannon K.\} and Cunningham, \{Julie M.\} and Scott Hebbring and Jacobsen, \{Steven J.\} and Cerhan, \{James R.\} and Slager, \{Susan L.\} and Blute, \{Michael L.\} and Schaid, \{Daniel J.\} and Thibodeau, \{Stephen N.\}",

note = "Funding Information: We thank D. Johnson for secretarial support. This study was supported by grants from the Public Health Service, US National Institutes of Health.",

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T1 - No association of germline alteration of MSR1 with prostate cancer risk

AU - Wang, Liang

AU - McDonnell, Shannon K.

AU - Cunningham, Julie M.

AU - Hebbring, Scott

AU - Jacobsen, Steven J.

AU - Cerhan, James R.

AU - Slager, Susan L.

AU - Blute, Michael L.

AU - Schaid, Daniel J.

AU - Thibodeau, Stephen N.

N1 - Funding Information: We thank D. Johnson for secretarial support. This study was supported by grants from the Public Health Service, US National Institutes of Health.

PY - 2003/10/1

Y1 - 2003/10/1

N2 - The macrophage scavenger receptor 1 gene (MSR1) was recently identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer. To confirm these findings, we screened MSR1 for germline mutations among individuals with familial prostate cancer and tested gene variants for associations in both sporadic and familial prostate cancer. Our results do not support MSR1 as a risk factor for prostate cancer.

AB - The macrophage scavenger receptor 1 gene (MSR1) was recently identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer. To confirm these findings, we screened MSR1 for germline mutations among individuals with familial prostate cancer and tested gene variants for associations in both sporadic and familial prostate cancer. Our results do not support MSR1 as a risk factor for prostate cancer.

UR - https://www.scopus.com/pages/publications/0141507056

UR - https://www.scopus.com/pages/publications/0141507056#tab=citedBy

U2 - 10.1038/ng1239

DO - 10.1038/ng1239

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VL - 35

SP - 128

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JO - Nature Genetics

JF - Nature Genetics

IS - 2

ER -

No association of germline alteration of MSR1 with prostate cancer risk

Abstract

ASJC Scopus subject areas

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