Neutrophil polycythemia rubra vera-1 expression in classic and atypical myeloproliferative disorders and laboratory correlates

Shireen Sirhan; Terra L. Lasho; Michelle A. Elliott; Ayalew Tefferi

Neutrophil polycythemia rubra vera-1 expression in classic and atypical myeloproliferative disorders and laboratory correlates

Shireen Sirhan, Terra L. Lasho, Michelle A. Elliott, Ayalew Tefferi

Hematology

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The current study of 153 subjects with both classic and atypical myeloproliferative disorders suggests that neutrophil polycythemia rubra vera-1 (PRV-1) over-expression is a non-specific feature of clonal myeloproliferation that displays significant correlation with leukocyte alkaline phosphatase score. These observations undermine the utility of the PRV-1 assay as a diagnostic test of additional value.

Original language	English (US)
Pages (from-to)	406-408
Number of pages	3
Journal	Haematologica
Volume	90
Issue number	3
State	Published - Mar 1 2005

Keywords

Diagnostic value
PRV-1
PRV-1 assay

ASJC Scopus subject areas

Hematology

Cite this

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title = "Neutrophil polycythemia rubra vera-1 expression in classic and atypical myeloproliferative disorders and laboratory correlates",

abstract = "The current study of 153 subjects with both classic and atypical myeloproliferative disorders suggests that neutrophil polycythemia rubra vera-1 (PRV-1) over-expression is a non-specific feature of clonal myeloproliferation that displays significant correlation with leukocyte alkaline phosphatase score. These observations undermine the utility of the PRV-1 assay as a diagnostic test of additional value.",

keywords = "Diagnostic value, PRV-1, PRV-1 assay",

author = "Shireen Sirhan and Lasho, {Terra L.} and Elliott, {Michelle A.} and Ayalew Tefferi",

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T1 - Neutrophil polycythemia rubra vera-1 expression in classic and atypical myeloproliferative disorders and laboratory correlates

AU - Sirhan, Shireen

AU - Lasho, Terra L.

AU - Elliott, Michelle A.

AU - Tefferi, Ayalew

PY - 2005/3/1

Y1 - 2005/3/1

N2 - The current study of 153 subjects with both classic and atypical myeloproliferative disorders suggests that neutrophil polycythemia rubra vera-1 (PRV-1) over-expression is a non-specific feature of clonal myeloproliferation that displays significant correlation with leukocyte alkaline phosphatase score. These observations undermine the utility of the PRV-1 assay as a diagnostic test of additional value.

AB - The current study of 153 subjects with both classic and atypical myeloproliferative disorders suggests that neutrophil polycythemia rubra vera-1 (PRV-1) over-expression is a non-specific feature of clonal myeloproliferation that displays significant correlation with leukocyte alkaline phosphatase score. These observations undermine the utility of the PRV-1 assay as a diagnostic test of additional value.

KW - Diagnostic value

KW - PRV-1

KW - PRV-1 assay

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M3 - Article

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AN - SCOPUS:15244354382

SN - 0390-6078

VL - 90

SP - 406

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JO - Haematologica

JF - Haematologica

IS - 3

ER -

Neutrophil polycythemia rubra vera-1 expression in classic and atypical myeloproliferative disorders and laboratory correlates

Abstract

Keywords

ASJC Scopus subject areas

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