TY - JOUR
T1 - Necrotizing myopathy with pipestem capillaries, microvascular deposition of the complement membrane attack complex (MAC), and minimal cellular infiltration
AU - Emslie-Smith, Alison M.
AU - Engel, Andrew G.
PY - 1991/6
Y1 - 1991/6
N2 - Three adult patients, two with undifferentiated connective tissue disease and one with carcinoma, had a distinctive pathologic reaction pattern consisting of necrotizing myopathy, minimal cellular infiltration, and a microangiopathy with thick “pipestem” vessels and microvascular deposits of complement membrane attack complex. Quantitative analysis revealed focal capillary depletion. This pattern represents an immune-mediated microangiopathy and is distinct from that observed in other inflammatory myopathies.
AB - Three adult patients, two with undifferentiated connective tissue disease and one with carcinoma, had a distinctive pathologic reaction pattern consisting of necrotizing myopathy, minimal cellular infiltration, and a microangiopathy with thick “pipestem” vessels and microvascular deposits of complement membrane attack complex. Quantitative analysis revealed focal capillary depletion. This pattern represents an immune-mediated microangiopathy and is distinct from that observed in other inflammatory myopathies.
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U2 - 10.1212/wnl.41.6.936
DO - 10.1212/wnl.41.6.936
M3 - Article
C2 - 2046947
AN - SCOPUS:0025733325
SN - 0028-3878
VL - 41
SP - 936
EP - 939
JO - Neurology
JF - Neurology
IS - 6
ER -