Natural orifice translumenal endoscopic surgery: Radical prostatectomy in the canine model

Amy E. Krambeck, Mitchell R. Humphreys, Paul E. Andrews, James E. Lingeman

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Purpose: The goal of this study is to demonstrate the feasibility of transurethral radical prostatectomy in the canine model. We describe the surgical procedure for natural orifice translumenal endoscopic surgery-radical prostatectomy (NOTES-RP). Materials and Methods: NOTES-RP was performed on six nonsurvival male canines. The 100 watt holmium:yttrium-aluminum-garne laser, 550 μm end-firing fiber, 28F laser resectoscope, 7F stabilizing catheter, and continuous irrigation were used to radically resect the prostate. A Vest vesicourethral anastomosis was performed using a laparoscopic suture device that was delivered through the nephroscope. In the initial cases, the prostate was removed manually; for the last two cases, the prostate was removed endoscopically with a tissue morcellator. Results: NOTES-RP was successfully executed in all canines. Visualization was not obscured by bleeding. Dissection times ranged from 40 to 120 minutes. Fluid absorption was problematic in cases lasting more than 1 hour, because of the intraperitoneal location of the canine prostate and bladder. Conclusions: The feasibility and technique of NOTES-RP was successfully demonstrated in the living canine model.

Original languageEnglish (US)
Pages (from-to)1493-1496
Number of pages4
JournalJournal of endourology
Issue number9
StatePublished - Sep 1 2010

ASJC Scopus subject areas

  • Urology


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