Abstract
Pre-analytical variability significantly impacts the reproducibility of liquid biopsy research, which is critical for precision medicine and biomedical research. This report highlights the challenges and variability in the pre-analytical processes of liquid biopsies, especially regarding extracellular vesicles (EVs), which are crucial for diagnostics in oncology. The MIBlood-EV initiative aims to standardize the reporting of pre-analytical variables and the quality control of plasma and serum samples to enhance reproducibility in EV research. By providing a comprehensive and flexible reporting framework, MIBlood-EV seeks to improve the reliability of EV studies and facilitate the development of evidence-based protocols, ultimately advancing the field of liquid biopsy research.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 62-64 |
| Number of pages | 3 |
| Journal | Biopreservation and Biobanking |
| Volume | 23 |
| Issue number | 1 |
| DOIs | |
| State | Published - Feb 1 2025 |
Keywords
- Best Practices
- Blood
- Extracellular Vesicles
- Liquid Biopsy
- Quality Control
- Reproducibility
- Standardization
ASJC Scopus subject areas
- Medicine (miscellaneous)
- General Biochemistry, Genetics and Molecular Biology
- Cell Biology