Methods for the assessment of small-bowel and colonic transit

Research output: Contribution to journalReview articlepeer-review

50 Scopus citations


Transit assessment of the small intestine and colon is relevant in the study of physiology, pathophysiology, and pharmacodynamics, and there is increasing use of small-bowel and colonic transit measurements in clinical practice as well. The main methods that are applied in clinical practice are substrate-hydrogen breath tests for small-bowel transit and radiopaque markers for colonic transit. Over the past 2-3 decades, scintigraphy has become the preferred standard in research studies, particularly for studies of pathophysiology and pharmacodynamics. New approaches include experimental stable isotope measurement of orocecal transit and the recently approved method using a wireless motility capsule that is validated as an accurate measurement of small-bowel and colonic transit.

Original languageEnglish (US)
Pages (from-to)113-123
Number of pages11
JournalSeminars in Nuclear Medicine
Issue number2
StatePublished - Mar 2012

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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