Melanoma mimicking Rosai-Dorfman disease

Daniel Y. Xie, Collin M. Costello, Helen J. Liang, Brett G. Thomas, David J. DiCaudo, Aaron R. Mangold

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Despite well-defined clinical and histopathological features of melanoma, atypical presentations mimicking other skin disorders can result in a delayed diagnosis or misdiagnosis and subsequent inappropriate treatment. Rosai-Dorfman disease (RDD) is a rare histiocytic disorder with unique clinical and histopathological features. We report a case of melanoma treated with cryotherapy that mimicked RDD both clinically and histopathologically. We compare this RDD-like melanoma to classic RDD, outlining the importance of clinicopathological correlation prior to treatment, as well as the potential pitfalls in diagnosis after cryotherapy of pigmented lesions.

Original languageEnglish (US)
Pages (from-to)355-359
Number of pages5
JournalJournal of Cutaneous Pathology
Issue number5
StatePublished - May 2018


  • Rosai-Dorfman disease
  • cryotherapy
  • melanoma
  • mimicker

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Dermatology


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