Megestrol acetate for the palliation of anorexia in advanced, incurable cancer patients

Farrah Mateen; Aminah Jatoi

doi:10.1016/j.clnu.2006.05.009

Megestrol acetate for the palliation of anorexia in advanced, incurable cancer patients

Farrah Mateen, Aminah Jatoi

Medical Oncology

Research output: Contribution to journal › Review article › peer-review

22 Scopus citations

Abstract

Anorexia, or loss of appetite, is a troubling symptom for many patients with advanced cancer. The early observation that breast cancer patients, who were prescribed megestrol acetate as a cancer treatment, went on to increase their appetite and gain weight has given rise to a large number of clinical trials that have tested this progestational drug as a palliative agent for the cancer anorexia/weight loss syndrome. This review focuses on these trials, summarizing their findings and providing a practical approach for prescribing megestrol acetate to advanced cancer patients who suffer from the cancer anorexia/weight loss syndrome.

Original language	English (US)
Pages (from-to)	711-715
Number of pages	5
Journal	Clinical Nutrition
Volume	25
Issue number	5
DOIs	https://doi.org/10.1016/j.clnu.2006.05.009
State	Published - Oct 2006

Keywords

Anorexia
Cancer
Megestrol acetate
Palliation

ASJC Scopus subject areas

Nutrition and Dietetics
Critical Care and Intensive Care Medicine

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10.1016/j.clnu.2006.05.009

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title = "Megestrol acetate for the palliation of anorexia in advanced, incurable cancer patients",

abstract = "Anorexia, or loss of appetite, is a troubling symptom for many patients with advanced cancer. The early observation that breast cancer patients, who were prescribed megestrol acetate as a cancer treatment, went on to increase their appetite and gain weight has given rise to a large number of clinical trials that have tested this progestational drug as a palliative agent for the cancer anorexia/weight loss syndrome. This review focuses on these trials, summarizing their findings and providing a practical approach for prescribing megestrol acetate to advanced cancer patients who suffer from the cancer anorexia/weight loss syndrome.",

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AB - Anorexia, or loss of appetite, is a troubling symptom for many patients with advanced cancer. The early observation that breast cancer patients, who were prescribed megestrol acetate as a cancer treatment, went on to increase their appetite and gain weight has given rise to a large number of clinical trials that have tested this progestational drug as a palliative agent for the cancer anorexia/weight loss syndrome. This review focuses on these trials, summarizing their findings and providing a practical approach for prescribing megestrol acetate to advanced cancer patients who suffer from the cancer anorexia/weight loss syndrome.

KW - Anorexia

KW - Cancer

KW - Megestrol acetate

KW - Palliation

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Megestrol acetate for the palliation of anorexia in advanced, incurable cancer patients

Abstract

Keywords

ASJC Scopus subject areas

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