TY - CHAP
T1 - Mechanisms of Action of Antiepileptic Drugs
AU - Britton, Jeffrey W.
AU - Zakaria, Tarek M.
AU - Benarroch, Eduardo
PY - 2011/3/18
Y1 - 2011/3/18
KW - Carbonic anhydrase inhibition - increasing concentration of intracellular hydrogen ions
KW - Epilepsy treatment, and selection - without firm understanding of pathophysiology of ictogenesis, or pharmaceutical mechanism of action
KW - Excitatory mechanisms targeted by AEDs
KW - Inhibitory mechanisms, targeted by AEDs - GABAA receptors/channels
KW - L-type calcium channels - and L-type calcium channels (Cav 1.2) in neuronal dendrites and cell bodies
KW - Main mechanisms of action of AEDs
KW - Mechanisms of action, early generation AEDs - understood after clinical use is established
KW - Newer AEDs, acting through mechanisms - reducing neuronal excitability, burst firing or abnormal synchronization
KW - Principles of medical management - mechanisms of action of antiepileptic drugs
KW - Valid antiepileptic drug (AED) options - in treatment of epilepsy and seizures
UR - http://www.scopus.com/inward/record.url?scp=84886001884&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84886001884&partnerID=8YFLogxK
U2 - 10.1002/9780470975039.ch9
DO - 10.1002/9780470975039.ch9
M3 - Chapter
AN - SCOPUS:84886001884
SN - 9780470741221
SP - 113
EP - 129
BT - Adult Epilepsy
PB - John Wiley and Sons
ER -