Mast cell pharyngitis as a cause of supraglottic edema

J. H. Butterfield, J. P. Marcoux, D. Weiler, S. G. Harner

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


A 30-year-old nonatopic woman had experienced a 9-year history of persistent symptoms of supraglottic edema. She had previously undergone epiglottectomy and excision of redundant left arytenoid tissue to improve her breathing and dysphagia. Uvular tissue was removed surgically at our clinic for histopathological examination of the excised tissues. This revealed diffuse infiltration by mast cells, many of which appeared degranulated. Uvular tissue from control patients undergoing uvulopalatopharyngoplasty for obstructive sleep apnea contained significantly fewer mast cells per high power field. To our knowledge such a degree of mast cell infiltration into supraglottic tissues has not been reported previously or associated with clinical symptoms.

Original languageEnglish (US)
Pages (from-to)88-91
Number of pages4
JournalArchives of Oto-Rhino-Laryngology
Issue number2
StatePublished - Mar 1988


  • Mast cells
  • Pharyngitis
  • Supraglottic edema
  • Uvula

ASJC Scopus subject areas

  • Otorhinolaryngology


Dive into the research topics of 'Mast cell pharyngitis as a cause of supraglottic edema'. Together they form a unique fingerprint.

Cite this