Management of Orbital Involvement in Sinonasal and Ventral Skull Base Malignancies

Gregory S. Neel, Thomas H. Nagel, Joseph M. Hoxworth, Devyani Lal

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


The orbit may be frequently involved by sinonasal or ventral skull base malignancy. This involvement bodes a poorer prognosis for survival. Multimodality therapy with surgery and radiation therapy is usually attempted to optimize local control and overall survival. Oncologic surgical resection with negative margins is critical to local control and survival. In the past, any involvement of the orbit was deemed to necessitate orbital sacrifice. However, contemporary studies show that in carefully selected cases, orbital preservation does not adversely impact survival. In addition, novel reconstructive techniques can help minimize complications and optimize functional and aesthetic outcomes.

Original languageEnglish (US)
Pages (from-to)347-364
Number of pages18
JournalOtolaryngologic Clinics of North America
Issue number2
StatePublished - Apr 1 2017


  • Endoscopic resection
  • Orbit
  • Orbit preservation
  • Orbital clearance
  • Orbital exenteration
  • Orbital invasion
  • Orbital sacrifice
  • Sinonasal malignancy

ASJC Scopus subject areas

  • Otorhinolaryngology


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