Management of local or regional non-nodal disease

Jennifer M. Racz, Matthew S. Block, Christian L. Baum, James W. Jakub

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Some melanomas develop a striking avidity for lymphatic spread. In spite of multiple recurrences, patients can remain years without visceral metastasis. There is clearly a biologic reason for this lymphotrophic pattern of growth and dissemination, which we have yet to uncover. In-transit metastases have widely diverse clinical presentations and can be a stubborn disease to cure. As a result, a host of treatments exist that should be tailored to the individual patient.

Original languageEnglish (US)
Pages (from-to)187-199
Number of pages13
JournalJournal of Surgical Oncology
Issue number2
StatePublished - Feb 1 2019


  • diphenylcyclopropenone
  • in transit
  • intralesional therapy
  • limb perfusion
  • melanoma, stage III
  • talimogene laherparepvec

ASJC Scopus subject areas

  • Surgery
  • Oncology


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