Management of chronic daily headache: Challenges in clinical practice

Joel R. Saper, David Dodick, Jonathan P. Gladstone

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations


Chronic daily headache (CHD) refers to a category of headache disorders that are characterized by headaches occurring on more than 15 days per month. This category is subdivided into long- and short-duration (>4 or <4 hours) CDH disorders based on the duration of individual headache attacks. Examples of long-duration CDH include transformed migraine (TM), chronic migraine (CM), new daily persistent headache (NDPH), acute medication overuse headache, and hemicrania continua (HC). The goal of this review is to enable clinicians to accurately diagnose and effectively manage patients with long-duration CDH. Patients with CDH often require an aggressive and comprehensive treatment approach that includes a combination of acute and preventive medications, as well as nondrug therapies.

Original languageEnglish (US)
Pages (from-to)S74-S85
Issue numberSUPPL. 1
StatePublished - Apr 2005


  • Chronic migraine
  • Clinical symptoms
  • Diagnosis
  • Headache
  • Treatment

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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