While the contractile properties of skeletal muscle have been studied extensively, relatively little is known about the elastic properties of muscle in vivo. Magnetic resonance elastography (MRE) is a phase contrast-based method for observing shear waves propagating in a material to determine its stiffness. In this work, MHE is applied to skeletal muscle under load to quantify the change in stiffness with loading. A mathematical model of muscle is developed that predicts a linear relationship between shear stiffness and muscle load. The MRE technique was applied to bovine muscle specimens (N = 10) and human biceps brachii in vivo (N = 5). Muscle stiffness increased linearly for both passive tension (14.5 ± 1.77 kPa/kg) and active tension, in which the increase in stiffness was dependent upon muscle size, as predicted by the model. A means of noninvasively assessing the viscoelastic properties of skeletal muscle in vivo may provide a useful method for studying muscle biomechanics in health and disease. J. Magn. Reson. Imaging 2001;13:269-276.
|Number of pages
|Journal of Magnetic Resonance Imaging
|Published - 2001
- Magnetic resonance imaging
- Mechanical properties
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging