Abstract
Aortic compliance and distensibility reflect overall wall stiffness, an extremely important and fundamental parameter altered in multiple diseases including hypertension, coronary artery disease, aortic aneurysm, and so on. Magnetic resonance elastography (MRE) is an innovative noninvasive imaging technique used to estimate the stiffness of soft tissues, including those comprising the wall of the aorta. This chapter describes (1) the principle of aortic MRE; (2) the motivation for use of aortic MRE for vascular applications; and (3) the current state-of-the-art in the development of aortic MRE, including the required hardware and MR pulse sequences. Finally, applications of aortic MRE and future potential application in characterizing coronary artery stiffness are also discussed.
Original language | English (US) |
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Title of host publication | Biomechanics of Coronary Atherosclerotic Plaque |
Subtitle of host publication | From Model to Patient |
Publisher | Elsevier |
Pages | 491-515 |
Number of pages | 25 |
ISBN (Electronic) | 9780128171950 |
ISBN (Print) | 9780128171967 |
DOIs | |
State | Published - Jan 1 2021 |
Keywords
- Abdominal aortic aneurysm
- Aortic MRE
- Aortic compliance
- Aortic stiffness
- Hypertension
- Magnetic resonance elastography
- Pulse wave velocity
- Systemic arterial hypertension
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)