TY - JOUR
T1 - Liver Transplantation for Hepatocellular Carcinoma
T2 - Expanding Frontiers and Building Bridges
AU - Masuoka, Howard C.
AU - Rosen, Charles B.
PY - 2011/5
Y1 - 2011/5
N2 - Despite significant advances in nonsurgical treatments of hepatocellular carcinoma, these approaches rarely result in cure. Surgery remains the mainstay of curative therapy for hepatocellular carcinoma. Liver transplantation, in particular, has emerged as one of the most beneficial therapeutic modalities. Questions remain, however, regarding hepatocellular carcinoma surveillance, the choice of surgical resection versus transplantation, the role of chemotherapy, optimal selection criteria for transplantation, and the role of ablative therapies to halt tumor progression and downsize tumors exceeding transplant criteria.
AB - Despite significant advances in nonsurgical treatments of hepatocellular carcinoma, these approaches rarely result in cure. Surgery remains the mainstay of curative therapy for hepatocellular carcinoma. Liver transplantation, in particular, has emerged as one of the most beneficial therapeutic modalities. Questions remain, however, regarding hepatocellular carcinoma surveillance, the choice of surgical resection versus transplantation, the role of chemotherapy, optimal selection criteria for transplantation, and the role of ablative therapies to halt tumor progression and downsize tumors exceeding transplant criteria.
KW - Cirrhosis
KW - Hepatocellular carcinoma
KW - Liver transplantation
KW - Organ allocation
UR - http://www.scopus.com/inward/record.url?scp=79959304232&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79959304232&partnerID=8YFLogxK
U2 - 10.1016/j.cld.2011.03.005
DO - 10.1016/j.cld.2011.03.005
M3 - Review article
C2 - 21689620
AN - SCOPUS:79959304232
SN - 1089-3261
VL - 15
SP - 385
EP - 393
JO - Clinics in liver disease
JF - Clinics in liver disease
IS - 2
ER -