Lipomatosis of the sciatic nerve: Typical and atypical MRI features

Bernadette Zhi Ying Wong, Kimberly K. Amrami, Doris E. Wenger, P. James B. Dyck, Bernd W. Scheithauer, Robert J. Spinner

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Lipomatosis of nerve, also known as fibrolipomatous hamartoma, is a rare condition of nerve, usually affecting the median nerve. The MRI appearance is characteristic. We describe two cases of lipomatosis of nerve involving the sciatic nerve, an extremely unusual location for this lesion, in patients with sciatic neuropathy. These cases share the typical features previously described in the literature for other nerves, but also contain atypical features not previously highlighted, relating to the variability in distribution and extent of the fatty deposition. Recognition of the MRI appearance of this entity is important in order to avoid unnecessary attempts at surgical resection of this lesion.

Original languageEnglish (US)
Pages (from-to)180-184
Number of pages5
JournalSkeletal Radiology
Issue number3
StatePublished - Mar 2006


  • Fibrolipomatous hamartoma
  • Lipomatosis of nerve
  • MRI
  • Macrodystrophia lipomatosa
  • Sciatic nerve

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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