Leveraging Existing and Soon-to-Be-Available Novel Diagnostics for Optimizing Outpatient Antibiotic Stewardship in Patients with Respiratory Tract Infections

Kelly A. Cawcutt; Robin Patel; Jeff Gerber; Angela M. Caliendo; Sara E. Cosgrove; Elizabeth Dodds Ashley; Piero Garzaro; Melissa Miller; Ebbing Lautenbach; Ritu Banerjee; Sarah E. Boyd; Mark H. Ebell; Thomas M. File; Erin H. Graf; Sara C. Keller; Sophia Koo; Daniel J. Livorsi; Larissa May; Rebekah Moehring; Frederick (Rick) Nolte; Benjamin Pinsky; Julie Szymczak; Tristan Timbrook; Ephraim Tsalik; Abinash Virk; Amanda Jezek; Jaclyn Levy; Rachel Zetts; Lauri Hicks; Joanna Wiecek; Rick Nettles; James Wittek; Patrick Murray; Christine Ginocchio

doi:10.1093/cid/ciaa1815

Leveraging Existing and Soon-to-Be-Available Novel Diagnostics for Optimizing Outpatient Antibiotic Stewardship in Patients with Respiratory Tract Infections

Kelly A. Cawcutt, Robin Patel, Jeff Gerber, Angela M. Caliendo, Sara E. Cosgrove, Elizabeth Dodds Ashley, Piero Garzaro, Melissa Miller, Ebbing Lautenbach, Ritu Banerjee, Sarah E. Boyd, Mark H. Ebell, Thomas M. File, Erin H. Graf, Sara C. Keller, Sophia Koo, Daniel J. Livorsi, Larissa May, Rebekah Moehring, Frederick (Rick) NolteBenjamin Pinsky, Julie Szymczak, Tristan Timbrook, Ephraim Tsalik, Abinash Virk, Amanda Jezek, Jaclyn Levy, Rachel Zetts, Lauri Hicks, Joanna Wiecek, Rick Nettles, James Wittek, Patrick Murray, Christine Ginocchio

Research output: Contribution to journal › Review article › peer-review

Abstract

Respiratory tract infections (RTIs) drive many outpatient encounters and, despite being predominantly viral, are associated with high rates of antibiotic prescriptions. With rising antibacterial resistance, optimization of prescribing of antibiotics in outpatients with RTIs is a critical need. Fortunately, this challenge arises at a time of increasing availability of novel RTI diagnostics to help discern which patients have bacterial infections warranting treatment. Effective implementation of antibiotic stewardship is needed, but optimal approaches for ambulatory settings are unknown. Future research needs are reviewed in this summary of a research summit convened by the Infectious Diseases Society of America in the fall of 2019.

Original language	English (US)
Pages (from-to)	E1115-E1121
Journal	Clinical Infectious Diseases
Volume	72
Issue number	12
DOIs	https://doi.org/10.1093/cid/ciaa1815
State	Published - Jun 15 2021

Keywords

antibiotic stewardship
antibiotics
outpatient
respiratory infections

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

Access to Document

10.1093/cid/ciaa1815

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Cawcutt, K. A., Patel, R., Gerber, J., Caliendo, A. M., Cosgrove, S. E., Ashley, E. D., Garzaro, P., Miller, M., Lautenbach, E., Banerjee, R., Boyd, S. E., Ebell, M. H., File, T. M., Graf, E. H., Keller, S. C., Koo, S., Livorsi, D. J., May, L., Moehring, R., ... Ginocchio, C. (2021). Leveraging Existing and Soon-to-Be-Available Novel Diagnostics for Optimizing Outpatient Antibiotic Stewardship in Patients with Respiratory Tract Infections. Clinical Infectious Diseases, 72(12), E1115-E1121. https://doi.org/10.1093/cid/ciaa1815

Cawcutt, KA, Patel, R, Gerber, J, Caliendo, AM, Cosgrove, SE, Ashley, ED, Garzaro, P, Miller, M, Lautenbach, E, Banerjee, R, Boyd, SE, Ebell, MH, File, TM, Graf, EH, Keller, SC, Koo, S, Livorsi, DJ, May, L, Moehring, R, Nolte, F, Pinsky, B, Szymczak, J, Timbrook, T, Tsalik, E, Virk, A, Jezek, A, Levy, J, Zetts, R, Hicks, L, Wiecek, J, Nettles, R, Wittek, J, Murray, P & Ginocchio, C 2021, 'Leveraging Existing and Soon-to-Be-Available Novel Diagnostics for Optimizing Outpatient Antibiotic Stewardship in Patients with Respiratory Tract Infections', Clinical Infectious Diseases, vol. 72, no. 12, pp. E1115-E1121. https://doi.org/10.1093/cid/ciaa1815

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title = "Leveraging Existing and Soon-to-Be-Available Novel Diagnostics for Optimizing Outpatient Antibiotic Stewardship in Patients with Respiratory Tract Infections",

abstract = "Respiratory tract infections (RTIs) drive many outpatient encounters and, despite being predominantly viral, are associated with high rates of antibiotic prescriptions. With rising antibacterial resistance, optimization of prescribing of antibiotics in outpatients with RTIs is a critical need. Fortunately, this challenge arises at a time of increasing availability of novel RTI diagnostics to help discern which patients have bacterial infections warranting treatment. Effective implementation of antibiotic stewardship is needed, but optimal approaches for ambulatory settings are unknown. Future research needs are reviewed in this summary of a research summit convened by the Infectious Diseases Society of America in the fall of 2019.",

keywords = "antibiotic stewardship, antibiotics, outpatient, respiratory infections",

author = "Cawcutt, {Kelly A.} and Robin Patel and Jeff Gerber and Caliendo, {Angela M.} and Cosgrove, {Sara E.} and Ashley, {Elizabeth Dodds} and Piero Garzaro and Melissa Miller and Ebbing Lautenbach and Ritu Banerjee and Boyd, {Sarah E.} and Ebell, {Mark H.} and File, {Thomas M.} and Graf, {Erin H.} and Keller, {Sara C.} and Sophia Koo and Livorsi, {Daniel J.} and Larissa May and Rebekah Moehring and Nolte, {Frederick (Rick)} and Benjamin Pinsky and Julie Szymczak and Tristan Timbrook and Ephraim Tsalik and Abinash Virk and Amanda Jezek and Jaclyn Levy and Rachel Zetts and Lauri Hicks and Joanna Wiecek and Rick Nettles and James Wittek and Patrick Murray and Christine Ginocchio",

note = "Publisher Copyright: {\textcopyright} 2020 The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.",

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doi = "10.1093/cid/ciaa1815",

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AU - Patel, Robin

AU - Gerber, Jeff

AU - Caliendo, Angela M.

AU - Cosgrove, Sara E.

AU - Ashley, Elizabeth Dodds

AU - Garzaro, Piero

AU - Miller, Melissa

AU - Lautenbach, Ebbing

AU - Banerjee, Ritu

AU - Boyd, Sarah E.

AU - Ebell, Mark H.

AU - File, Thomas M.

AU - Graf, Erin H.

AU - Keller, Sara C.

AU - Koo, Sophia

AU - Livorsi, Daniel J.

AU - May, Larissa

AU - Moehring, Rebekah

AU - Nolte, Frederick (Rick)

AU - Pinsky, Benjamin

AU - Szymczak, Julie

AU - Timbrook, Tristan

AU - Tsalik, Ephraim

AU - Virk, Abinash

AU - Jezek, Amanda

AU - Levy, Jaclyn

AU - Zetts, Rachel

AU - Hicks, Lauri

AU - Wiecek, Joanna

AU - Nettles, Rick

AU - Wittek, James

AU - Murray, Patrick

AU - Ginocchio, Christine

N1 - Publisher Copyright: © 2020 The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

PY - 2021/6/15

Y1 - 2021/6/15

N2 - Respiratory tract infections (RTIs) drive many outpatient encounters and, despite being predominantly viral, are associated with high rates of antibiotic prescriptions. With rising antibacterial resistance, optimization of prescribing of antibiotics in outpatients with RTIs is a critical need. Fortunately, this challenge arises at a time of increasing availability of novel RTI diagnostics to help discern which patients have bacterial infections warranting treatment. Effective implementation of antibiotic stewardship is needed, but optimal approaches for ambulatory settings are unknown. Future research needs are reviewed in this summary of a research summit convened by the Infectious Diseases Society of America in the fall of 2019.

AB - Respiratory tract infections (RTIs) drive many outpatient encounters and, despite being predominantly viral, are associated with high rates of antibiotic prescriptions. With rising antibacterial resistance, optimization of prescribing of antibiotics in outpatients with RTIs is a critical need. Fortunately, this challenge arises at a time of increasing availability of novel RTI diagnostics to help discern which patients have bacterial infections warranting treatment. Effective implementation of antibiotic stewardship is needed, but optimal approaches for ambulatory settings are unknown. Future research needs are reviewed in this summary of a research summit convened by the Infectious Diseases Society of America in the fall of 2019.

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Leveraging Existing and Soon-to-Be-Available Novel Diagnostics for Optimizing Outpatient Antibiotic Stewardship in Patients with Respiratory Tract Infections

Abstract

Keywords

ASJC Scopus subject areas

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