TY - JOUR
T1 - Left Ventricular Form and Function Revisited
T2 - Applied Translational Science to Cardiovascular Ultrasound Imaging
AU - Sengupta, Partho P.
AU - Krishnamoorthy, Vijay K.
AU - Korinek, Josef
AU - Narula, Jagat
AU - Vannan, Mani A.
AU - Lester, Steven J.
AU - Tajik, Jamil A.
AU - Seward, James B.
AU - Khandheria, Bijoy K.
AU - Belohlavek, Marek
N1 - Funding Information:
Supported by grant HL68573 and, in parts, HL68555 and HL70363 from the National Institutes of Health and Grant in Aid from the American Society of Echocardiography.
PY - 2007/5
Y1 - 2007/5
N2 - Doppler tissue imaging (DTI) and DTI-derived strain imaging are robust physiologic tools used for the noninvasive assessment of regional myocardial function. As a result of high temporal and spatial resolution, regional function can be assessed for each phase of the cardiac cycle and within the transmural layers of the myocardial wall. Newer techniques that measure myocardial motion by speckle tracking in gray-scale images have overcome the angle dependence of DTI strain, allowing for measurement of 2-dimensional strain and cardiac rotation. DTI, DTI strain, and speckle tracking may provide unique information that deciphers the deformation sequence of complexly oriented myofibers in the left ventricular wall. The data are, however, limited. This review examines the structure and function of the left ventricle relative to the potential clinical application of DTI and speckle tracking in assessing the global mechanical sequence of the left ventricle in vivo.
AB - Doppler tissue imaging (DTI) and DTI-derived strain imaging are robust physiologic tools used for the noninvasive assessment of regional myocardial function. As a result of high temporal and spatial resolution, regional function can be assessed for each phase of the cardiac cycle and within the transmural layers of the myocardial wall. Newer techniques that measure myocardial motion by speckle tracking in gray-scale images have overcome the angle dependence of DTI strain, allowing for measurement of 2-dimensional strain and cardiac rotation. DTI, DTI strain, and speckle tracking may provide unique information that deciphers the deformation sequence of complexly oriented myofibers in the left ventricular wall. The data are, however, limited. This review examines the structure and function of the left ventricle relative to the potential clinical application of DTI and speckle tracking in assessing the global mechanical sequence of the left ventricle in vivo.
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U2 - 10.1016/j.echo.2006.10.013
DO - 10.1016/j.echo.2006.10.013
M3 - Review article
C2 - 17485001
AN - SCOPUS:34247627356
SN - 0894-7317
VL - 20
SP - 539
EP - 551
JO - Journal of the American Society of Echocardiography
JF - Journal of the American Society of Echocardiography
IS - 5
ER -