LASH: A Review of the Current Literature

William Kingston, Rashmi Halker

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Purpose of Review: The purpose of this review is to evaluate and explain our current understanding of a very rare disorder, long-lasting autonomic symptoms with associated hemicranias (LASH). Recent Findings: At present, there are four known cases in the literature of LASH. Its characteristics and reported response to indomethacin link it most closely to the trigeminal autonomic cephalalgias (TACs). Its pathophysiology and epidemiology remain unclear. Summary: Variance in the pain and autonomic symptom relationship in the existing TAC literature along with the reports of TAC sine headache suggests that LASH may represent a far end of the spectrum of TACs, with most similarities to paroxysmal hemicrania (PH) and hemicrania continua (HC).

Original languageEnglish (US)
Article number36
JournalCurrent pain and headache reports
Issue number8
StatePublished - Aug 1 2017


  • Indomethacin
  • Lash
  • Trigeminal autonomic cephalalgia

ASJC Scopus subject areas

  • Clinical Neurology
  • Anesthesiology and Pain Medicine


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