Laparoscopy vs. Robotic Surgery for Endometriosis (LAROSE): a multicenter, randomized, controlled trial

Enrique Soto, Thanh Ha Luu, Xiaobo Liu, Javier F. Magrina, Megan N. Wasson, Jon I. Einarsson, Sarah L. Cohen, Tommaso Falcone

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Objective To determine whether the use of the robot for surgical treatment of endometriosis is better than traditional laparoscopy in terms of operative length, perioperative parameters, and quality of life outcomes. Design Multicenter, randomized clinical trial. Setting University teaching hospitals. Patient(s) Women aged >18 years with suspected endometriosis who elected to undergo surgical management. Intervention(s) Randomization to conventional or robot-assisted laparoscopic removal of endometriosis. Main Outcome Measure(s) The primary outcome measured was operative time. Secondary outcomes were perioperative complications and quality of life. Result(s) The mean operative time for robotic vs. laparoscopic surgery for endometriosis was 106.6 ± 48.4 minutes vs. 101.6 ± 63.2 minutes. There were no differences in blood loss, intraoperative or postoperative complications, or rates of conversion to laparotomy in the two arms. Both groups reported significant improvement on condition-specific quality of life outcomes at 6 weeks and 6 months. Conclusion(s) There were no differences in perioperative outcomes between robotic and conventional laparoscopy. Clinical Trial Registration Number NCT01556204.

Original languageEnglish (US)
Pages (from-to)996-1002.e3
JournalFertility and sterility
Issue number4
StatePublished - Apr 1 2017


  • Endometriosis
  • laparoscopy
  • perioperative outcomes
  • quality of life
  • robot-assisted surgery

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology


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