Kliniczna i genetyczna róznorodność reumatoidalnego zapalenia stawów.

Translated title of the contribution: Clinical and genetic heterogeneity of rheumatoid arthritis

P. A. Klimiuk, C. M. Weyand, S. Sierakowski, J. J. Goronzy

Research output: Contribution to journalReview articlepeer-review


The diagnostic category of rheumatoid arthritis, a syndrome of chronic inflammatory disease of the synovial membrane and of extraarticular tissues, covers a broad spectrum of clinical phenotypes. Here we propose that distinct combinations of disease risk genes produce heterogeneity of rheumatoid disease. Recognition of this genetic and clinical heterogeneity has immediate implications as it provides the opportunity to develop selective therapies for the different variants of disease.

Translated title of the contributionClinical and genetic heterogeneity of rheumatoid arthritis
Original languagePolish
Pages (from-to)845-853
Number of pages9
JournalPostepy Higieny i Medycyny Doswiadczalnej
Issue number6
StatePublished - 2000

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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