KDIGO Controversies Conference on onco-nephrology: understanding kidney impairment and solid-organ malignancies, and managing kidney cancer

Camillo Porta, Aristotelis Bamias, Farhad R. Danesh, Alicja Dębska-Ślizień, Maurizio Gallieni, Morie A. Gertz, Jan T. Kielstein, Petra Tesarova, Germaine Wong, Michael Cheung, David C. Wheeler, Wolfgang C. Winkelmayer, Jolanta Małyszko, Ali K. Abu-Alfa, Hatem Amer, Gernot Beutel, Jeremy Chapman, Xiaohong Chen, Jerzy Chudek, Laura CosmaiRomano Danesi, Filippo De Stefano, Kunitoshi Iseki, Edgar A. Jaimes, Kenar D. Jhaveri, Artur Jurczyszyn, Rümeyza Kazancioğlu, Abhijat Kitchlu, Christian Kollmannsberger, Amit Lahoti, Yang Li, Manuel Macía, Takeshi Matsubara, Dionysios Mitropoulos, Eisei Noiri, Mark A. Perazella, Pierre Ronco, Mitchell H. Rosner, Maria Jose Soler Romeo, Ben Sprangers, Walter M. Stadler, Paul E. Stevens, Tesař ladimír Tesař, Verônica Torres da Costa e Silva, David H. Vesole, Anitha Vijayan, Ondřej Viklický, Biruh T. Workeneh, Motoko Yanagita, Elena Zakharova

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


The association between kidney disease and cancer is multifaceted and complex. Persons with chronic kidney disease (CKD) have an increased incidence of cancer, and both cancer and cancer treatments can cause impaired kidney function. Renal issues in the setting of malignancy can worsen patient outcomes and diminish the adequacy of anticancer treatments. In addition, the oncology treatment landscape is changing rapidly, and data on tolerability of novel therapies in patients with CKD are often lacking. Caring for oncology patients has become more specialized and interdisciplinary, currently requiring collaboration among specialists in nephrology, medical oncology, critical care, clinical pharmacology/pharmacy, and palliative care, in addition to surgeons and urologists. To identify key management issues in nephrology relevant to patients with malignancy, KDIGO (Kidney Disease: Improving Global Outcomes) assembled a global panel of multidisciplinary clinical and scientific expertise for a controversies conference on onco-nephrology in December 2018. This report covers issues related to kidney impairment and solid organ malignancies as well as management and treatment of kidney cancer. Knowledge gaps, areas of controversy, and research priorities are described.

Original languageEnglish (US)
Pages (from-to)1108-1119
Number of pages12
JournalKidney international
Issue number5
StatePublished - Nov 2020


  • glomerular filtration rate
  • nephrotoxicity
  • oncology
  • renal cell carcinoma

ASJC Scopus subject areas

  • Nephrology


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