Isolation of a cDNA encoding the chicken homologue of the human calcium-modulating cyclophilin ligand

Richard J. Bram

doi:10.1016/0378-1119(96)00081-9

Isolation of a cDNA encoding the chicken homologue of the human calcium-modulating cyclophilin ligand

Richard J. Bram

Pediatric and Adolescent Medicine

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

In order to identify important regions of the human CAML (calcium-modulating cyclophilin ligand) protein, a cDNA encoding the chicken homologue was isolated using low-stringency hybridization screening of a T-lymphocyte cDNA library. The deduced amino acid sequences of chicken and human CAML show areas of extensive conservation, suggesting an evolutionarily important role in signaling.

Original language	English (US)
Pages (from-to)	307-309
Number of pages	3
Journal	Gene
Volume	174
Issue number	2
DOIs	https://doi.org/10.1016/0378-1119(96)00081-9
State	Published - 1996

Keywords

CAML
Calcineurin
Capacitative calcium influx
Cyclosporin
Immunophilin
Signal transduction
T-cell activation

ASJC Scopus subject areas

Genetics

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10.1016/0378-1119(96)00081-9

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@article{93f7d18c7071477c8b1f9ead86252b9c,

title = "Isolation of a cDNA encoding the chicken homologue of the human calcium-modulating cyclophilin ligand",

abstract = "In order to identify important regions of the human CAML (calcium-modulating cyclophilin ligand) protein, a cDNA encoding the chicken homologue was isolated using low-stringency hybridization screening of a T-lymphocyte cDNA library. The deduced amino acid sequences of chicken and human CAML show areas of extensive conservation, suggesting an evolutionarily important role in signaling.",

keywords = "CAML, Calcineurin, Capacitative calcium influx, Cyclosporin, Immunophilin, Signal transduction, T-cell activation",

author = "Bram, \{Richard J.\}",

note = "Funding Information: This work was supported in part by grant BE-234 from the American Cancer Society, Cancer Center CORE grant CA-21765 from the National Institutes of Health and by the American Lebanese Syrian Associated Charities (ALSAC). R.J.B. is a James S. McDonnell Foundation Scholar in the program for Molecular Medicine in Cancer Research.",

year = "1996",

doi = "10.1016/0378-1119(96)00081-9",

language = "English (US)",

volume = "174",

pages = "307--309",

journal = "Gene",

issn = "0378-1119",

publisher = "Elsevier B.V.",

number = "2",

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T1 - Isolation of a cDNA encoding the chicken homologue of the human calcium-modulating cyclophilin ligand

AU - Bram, Richard J.

N1 - Funding Information: This work was supported in part by grant BE-234 from the American Cancer Society, Cancer Center CORE grant CA-21765 from the National Institutes of Health and by the American Lebanese Syrian Associated Charities (ALSAC). R.J.B. is a James S. McDonnell Foundation Scholar in the program for Molecular Medicine in Cancer Research.

PY - 1996

Y1 - 1996

N2 - In order to identify important regions of the human CAML (calcium-modulating cyclophilin ligand) protein, a cDNA encoding the chicken homologue was isolated using low-stringency hybridization screening of a T-lymphocyte cDNA library. The deduced amino acid sequences of chicken and human CAML show areas of extensive conservation, suggesting an evolutionarily important role in signaling.

AB - In order to identify important regions of the human CAML (calcium-modulating cyclophilin ligand) protein, a cDNA encoding the chicken homologue was isolated using low-stringency hybridization screening of a T-lymphocyte cDNA library. The deduced amino acid sequences of chicken and human CAML show areas of extensive conservation, suggesting an evolutionarily important role in signaling.

KW - CAML

KW - Calcineurin

KW - Capacitative calcium influx

KW - Cyclosporin

KW - Immunophilin

KW - Signal transduction

KW - T-cell activation

UR - https://www.scopus.com/pages/publications/0029823256

UR - https://www.scopus.com/pages/publications/0029823256#tab=citedBy

U2 - 10.1016/0378-1119(96)00081-9

DO - 10.1016/0378-1119(96)00081-9

M3 - Article

C2 - 8890752

AN - SCOPUS:0029823256

SN - 0378-1119

VL - 174

SP - 307

EP - 309

JO - Gene

JF - Gene

IS - 2

ER -

Isolation of a cDNA encoding the chicken homologue of the human calcium-modulating cyclophilin ligand

Abstract

Keywords

ASJC Scopus subject areas

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