Isolated Whipple disease of the brain resembling a tumour

James L. Frazier, Alfredo Quinones-Hinojosa

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Introduction: Isolated Whipple disease of the central nervous system is a rare occurrence. Migratory arthralgias and gastrointestinal problems, including malabsorption, abdominal pain, diarrhea, and weight loss, are common presenting symptoms. Discussion: For those patients with systemic signs and symptoms of Whipple disease, 6% to 43% will have clinically manifested CNS involvement that may include alterations in personality, ataxia, and dementia. We report our experience with a patient, who was successfully treated for Whipple disease 12 years prior to presentation and had a magnetic resonance image of the brain that revealed two solitary lesions resembling a tumor upon presentation.

Original languageEnglish (US)
Pages (from-to)173-175
Number of pages3
JournalActa Neurochirurgica
Issue number2
StatePublished - Feb 2009


  • Brain
  • Central nervous system
  • Tumour
  • Whipple disease
  • Whipple's bacilli

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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