Isolated angioedema of the bowel caused by aspirin

Karim Osman, Ayse Tuba Kendi, Daniel Maselli

Research output: Contribution to journalArticlepeer-review


Angioedema is a self-limited, localized tissue swelling, resulting from fluid extravasation into interstitial spaces. It may occur in isolation or be accompanied by urticaria and/or anaphylaxis. The phenomenon has been linked to multiple medications, including non-steroidal anti-inflammatory drugs (NSAIDs) and angiotensin-converting enzyme inhibitors (ACEIs). NSAID-induced angioedema is observed in < 0.3% of patients taking NSAIDs. While isolated visceral angioedema has been reported from ACEIs, it has not been documented from NSAID use, particularly aspirin usage. Here, we report a case of isolated visceral angioedema attributed to aspirin use.

Original languageEnglish (US)
Pages (from-to)1096-1102
Number of pages7
JournalClinical Journal of Gastroenterology
Issue number4
StatePublished - Aug 2021


  • Angioedema
  • Aspirin
  • Non-steroidal anti-inflammatory drugs
  • Small bowel

ASJC Scopus subject areas

  • Gastroenterology


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