Intravascular lipoleiomyomatosis: A report of two cases

Robert J. Brescia, Henry D. Tazelaar, John Hobbs, Alexander W. Miller

Research output: Contribution to journalArticlepeer-review

38 Scopus citations


Two cases of intravascular leiomyomatosis (IVL) with histologic features of a lipoleiomyoma (LPL) are reported. Both tumors arose from preexisting uterine leiomyomata. One tumor was found incidentally in a uterus removed for leiomyomata. The other tumor extended up the inferior vena cava into the right side of the heart and presented as a cardiac mass. Although LPL is considered to be a benign lesion, IVL recurs in approximately 10% of reported cases, and must be distinguished from low-grade endometrial stromal sarcoma and leiomyosarcoma with vascular invasion. The combination of features in these cases lends support to the theory that IVL may arise by intravascular extension of a preexisting leiomyoma.

Original languageEnglish (US)
Pages (from-to)252-256
Number of pages5
JournalHuman Pathology
Issue number3
StatePublished - Mar 1989


  • intravascular leiomyomatosis
  • leiomyoma
  • lipoleiomyoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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