Interstitial pneumonitis associated with 'crack' cocaine abuse

A. E. O'Donnell, F. G. Mappin, T. J. Sebo, H. Tazelaar

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


A 33-year-old woman developed acute bilateral pulmonary infiltrates after the intense use of rock cocaine (crack). She subsequently had progressive deterioration of pulmonary function to the point of being ventilator-dependent. Open lung biopsy showed a chronic interstitial pneumonia with extensive accumulation of free silica within histiocytes associated with mild pulmonary fibrosis. This pattern of interstitial pneumonia has not been previously reported in crack users.

Original languageEnglish (US)
Pages (from-to)1155-1157
Number of pages3
Issue number4
StatePublished - 1991

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine


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