Interscan registration using navigator echoes

Edward Brian Welch, Armando Manduca, Roger C. Grimm, Clifford R. Jack

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


A common problem in clinical MRI is anatomic misalignment of imaging slices across successive examinations. This unnecessarily complicates the radiologic assessment of anatomic change over time on serial MRI studies. To address this problem, spherical navigator echoes, which can detect rigid body motion in all six degrees of freedom, were used to guide spatial location and orientation adjustments to an exam prescription to match the reference frame of images acquired in an earlier exam. An initial linear navigator echo is also necessary to effect coarse Z translation adjustments prior to fine six degrees of freedom adjustment with a spherical navigator echo. Results of this technique are presented for head image volumes of five volunteers. Each volunteer was imaged on two scanners. In all cases, the reference frame adjustments provided by the navigator echoes substantially improved the alignment of the latter exam and performed well compared to retrospective image-based registration.

Original languageEnglish (US)
Pages (from-to)1448-1452
Number of pages5
JournalMagnetic Resonance in Medicine
Issue number6
StatePublished - Dec 2004


  • Interscan alignment
  • Linear navigator echo
  • Motion correction
  • Rotation
  • Spherical navigator echo
  • Translation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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