Insight into regulatory factor targeting to transcriptionally active subnuclear sites

Gary S. Stein; André J. Van Wijnen; Janet L. Stein; Jane B. Lian; Amjad Javed; Sandra McNeil; Shirwin M. Pockwinse

doi:10.1006/excr.1999.4680

Insight into regulatory factor targeting to transcriptionally active subnuclear sites

Gary S. Stein, André J. Van Wijnen, Janet L. Stein, Jane B. Lian, Amjad Javed, Sandra McNeil, Shirwin M. Pockwinse

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5 Scopus citations

Abstract

Mechanisms that coordinate the spatial organization of genes and regulatory proteins within the three-dimensional context of nuclear architecture contribute to the sorting of regulatory information as well as the assembly and activity of sites within the nucleus that support gene expression. In this article we will present an overview of experimental approaches that provide insight into the trafficking of the hematopoietic and bone-specific AML/CBF family of regulatory factors to transcriptionally active subnuclear sites.

Original language	English (US)
Pages (from-to)	110-116
Number of pages	7
Journal	Experimental Cell Research
Volume	253
Issue number	1
DOIs	https://doi.org/10.1006/excr.1999.4680
State	Published - Nov 25 1999

Keywords

AML/CBFα
Gene expression
Nuclear domains
Transcriptional control

ASJC Scopus subject areas

Cell Biology

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10.1006/excr.1999.4680

Cite this

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title = "Insight into regulatory factor targeting to transcriptionally active subnuclear sites",

abstract = "Mechanisms that coordinate the spatial organization of genes and regulatory proteins within the three-dimensional context of nuclear architecture contribute to the sorting of regulatory information as well as the assembly and activity of sites within the nucleus that support gene expression. In this article we will present an overview of experimental approaches that provide insight into the trafficking of the hematopoietic and bone-specific AML/CBF family of regulatory factors to transcriptionally active subnuclear sites.",

keywords = "AML/CBFα, Gene expression, Nuclear domains, Transcriptional control",

author = "Stein, {Gary S.} and {Van Wijnen}, {Andr{\'e} J.} and Stein, {Janet L.} and Lian, {Jane B.} and Amjad Javed and Sandra McNeil and Pockwinse, {Shirwin M.}",

note = "Funding Information: Components of the work reported in this review were supported by National Institutes of Health Grants AR45688 and AR45689. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the National Institutes of Health. The authors are appreciative of the editorial assistance from Elizabeth Bronstein with development of the manuscript.",

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AU - Stein, Gary S.

AU - Van Wijnen, André J.

AU - Stein, Janet L.

AU - Lian, Jane B.

AU - Javed, Amjad

AU - McNeil, Sandra

AU - Pockwinse, Shirwin M.

N1 - Funding Information: Components of the work reported in this review were supported by National Institutes of Health Grants AR45688 and AR45689. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the National Institutes of Health. The authors are appreciative of the editorial assistance from Elizabeth Bronstein with development of the manuscript.

PY - 1999/11/25

Y1 - 1999/11/25

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KW - AML/CBFα

KW - Gene expression

KW - Nuclear domains

KW - Transcriptional control

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Insight into regulatory factor targeting to transcriptionally active subnuclear sites

Abstract

Keywords

ASJC Scopus subject areas

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