Infection associated with prosthetic joints

Jose L. Del Pozo, Robin Patel

Research output: Contribution to journalArticlepeer-review

545 Scopus citations


A 62-year-old woman with osteoarthritis presents with a 7-month history of progressively worsening left hip pain radiating to the groin, 8 months after undergoing total left-hip arthroplasty. The pain has not responded to nonsteroidal antiinflammatory drugs. Physical examination reveals a sinus tract overlying her left hip. Her leukocyte count is 8000 per cubic millimeter, and the C-reactive protein (CRP) level is 15.5 mg per liter. A radiograph shows loosening of the prosthesis at the bone-cement interface. Synovial-fluid aspirate shows 15×103 cells per cubic millimeter (89% neutrophils); cultures of an aspirate from the hip grow Staphylococcus epidermidis. How should her case be managed?

Original languageEnglish (US)
Pages (from-to)787-794
Number of pages8
JournalNew England Journal of Medicine
Issue number8
StatePublished - Aug 20 2009

ASJC Scopus subject areas

  • General Medicine


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