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Impact of prior nicotine replacement therapy on smoking cessation efficacy

  • Michael J. Durcan
  • , Jonathan White
  • , Douglas E. Jorenby
  • , Michael C. Fiore
  • , Stephen I. Rennard
  • , Scott J. Leischow
  • , Mitchell A. Nides
  • , John A. Ascher
  • , J. Andrew Johnston

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To examine previous use of nicotine replacement therapy (NRT) on the smoking-cessation efficacy of bupropion sustained release (SR). Methods: Secondary analysis of a parallel-group, randomized, double-blind, placebo-controlled study. Smokers who had, based on self-report, no previous history of NRT (N=453) or who had used NRT at least once (N=440) were randomized to receive placebo, bupropion SR, nicotine transdermal system (NTS), or a combination of bupropion SR and NTS. Results: Bupropion SR showed similar efficacy in participants with or without previous use of NRT. Conclusion: Bupropion SR is effective in promoting smoking abstinence regardless of prior NRT use.

Original languageEnglish (US)
Pages (from-to)213-220
Number of pages8
JournalAmerican Journal of Health Behavior
Volume26
Issue number3
DOIs
StatePublished - 2002

ASJC Scopus subject areas

  • Health(social science)
  • Social Psychology
  • Public Health, Environmental and Occupational Health

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