Impact of fentanyl in lieu of meperidine on endoscopy unit efficiency: A prospective comparative study in patients undergoing EGD

Ivana Dzeletovic, M. Edwyn Harrison, Michael D. Crowell, Francisco C. Ramirez, Catherine R. Yows, Lucinda A. Harris, Shabana F. Pasha, Suryakanth R. Gurudu, Jonathan A. Leighton, Russell I. Heigh

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Background: Turnaround time is an important component of endoscopy unit efficiency. Any reduction in the total time from patient arrival in the endoscopy room to departure from the recovery area may translate into better endoscopy unit efficiency. Objective: To evaluate the effects on endoscopy unit efficiency of a change in narcotic choice for moderate sedation in patients undergoing EGD at an ambulatory surgery center. Design: Prospective, comparative, quality-improvement project. Setting: Endoscopy unit of a tertiary-care academic medical center. Patients: We enrolled consecutive patients (n = 1963) who underwent outpatient EGD by 1 of 5 endoscopists between November 2008 and November 2010. Intervention: Moderate sedation with midazolam plus fentanyl versus meperidine. Main Outcome Measurements: Sedation-dependent endoscopy unit efficiency and total procedure time (induction-to-intubation, intubation-to-extubation, and extubation-to-discharge). Results: Fentanyl was associated with reduced total procedure time by 10.1 minutes resulting from both shorter induction-to-intubation time and extubation-to-discharge time (P <.001). The mean (± SD) sedation-dependent endoscopy unit efficiency was 3.2 (± 1.9) procedures per hour for the meperidine group and 3.9 (± 2.7) procedures per hour for the fentanyl group (P =.012); this would translate into possibly increasing the endoscopy suite efficiency by 22%. Based on dosage equivalency conversion, equal doses of fentanyl and meperidine were used. No sedation-related complications or need for reversal agents were recorded. Limitations: No randomization was performed. Conclusion: Compared with meperidine, fentanyl in combination with midazolam was associated with significantly shorter total procedure time. By improving the turnaround time, sedation-dependent endoscopy unit efficiency may be improved by 22%.

Original languageEnglish (US)
Pages (from-to)883-887
Number of pages5
JournalGastrointestinal endoscopy
Issue number6
StatePublished - Jun 2013

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology


Dive into the research topics of 'Impact of fentanyl in lieu of meperidine on endoscopy unit efficiency: A prospective comparative study in patients undergoing EGD'. Together they form a unique fingerprint.

Cite this