Impact of cefepime susceptible-dose-dependent mic for enterobacteriaceae on reporting and prescribing

Christina G. Rivera, Prasanna P. Narayanan, Robin Patel, Lynn L. Estes

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The CLSI cefepime breakpoints were revised to include a susceptible-dose-dependent (SDD) category for Enterobacteriaceae, with the intention that higher cefepime doses be used for these isolates. In this study, 1.6% of Enterobacteriaceae isolates were reported as SDD, with Escherichia coli the most common SDD organism. Cefepime was prescribed in three cases (4.8%); the majority of SDD isolates were treated with a carbapenem. Enterobacteriaceae with cefepime SDD MICs were not commonly treated with cefepime at our institution.

Original languageEnglish (US)
Pages (from-to)3854-3855
Number of pages2
JournalAntimicrobial Agents and Chemotherapy
Volume60
Issue number6
DOIs
StatePublished - Jun 2016

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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