Immature teratoma of the pineal gland with isochromosome 12p

Paola Dal Cin, Angelo P. Dei Tos, Heng Qi, Caterina Giannini, Alberto Furlanetto, Pier Luigi Longatti, Peter Marynen, Herman Van den Berghe

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


An immature teratoma arising in the pineal gland in a 27-year-old male was shown to present an isochromosome 12p as evidenced by cytogenetic and fluorescence in situ hybridization analysis. As i(12p) is characteristic of gonadal germ cell tumors, this case indicates that similar genetic pathways may operate in gonadal and intracranial teratomas.

Original languageEnglish (US)
Pages (from-to)107-110
Number of pages4
JournalActa neuropathologica
Issue number1
StatePublished - Dec 1997


  • Brain tumor
  • Germ cell tumor
  • Immature teratoma
  • Isochromosome 12p

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Clinical Neurology
  • Cellular and Molecular Neuroscience


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