Identification of three novel RB1 mutations in Brazilian patients with retinoblastoma by "exon by exon" PCR mediated SSCP analysis

Keyphrases

• Exon 100%
• Codon 100%
• SSCP Analysis 100%
• Retinoblastoma 100%
• Brazilian Patients 100%
• RB1 mutation 100%
• Ligand-binding Domain 60%
• Paraffin Wax 40%
• Specific mutation 20%
• DNA Extracts 20%
• Missense 20%
• Mutation Screening 20%
• Polymerase Chain Reaction 20%
• Novel mutation 20%
• Exon 2 20%
• DNA Sequencing 20%
• Nonsense 20%
• Coding Region 20%
• Genetic Counseling 20%
• Formalin-fixed 20%
• Exon Splicing 20%
• Single-strand Conformation Polymorphism 20%
• Frameshift 20%
• Mutation Hotspots 20%
• Exonic 20%
• Stop Codon 20%
• Single-base Substitution 20%
• Exon 20 20%
• Mutational Target 20%
• Polymorphism Analysis 20%

Biochemistry, Genetics and Molecular Biology

• Paraffin Wax 28%