Iatrogenic cerebellar implantation of a vestibular schwannoma: Case report

Todd A. Patrick, Caterina Giannini, Michael J. Ebersold, Michael J. Link

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Metastatic seeding or iatrogenic implantation of numerous types of primary central nervous system tumors, typically along cerebrospinal fluid pathways, is a frequently described albeit rare phenomenon and has never been reported in association with vestibular schwannoma (VS). The authors present a case of inadvertent surgical implantation of VS into the cerebellar hemisphere during resection of a recurrent VS in the cerebellopontine angle and internal auditory canal. A 42-year-old man presented with a 2.5-cm right VS that was removed without complication via a retrosigmoid approach. Routine imaging performed 5 years later revealed a 1.5-cm recurrence of the VS that was subsequently removed by reopening the retrosigmoid craniotomy. Five years later - 10 years after initial presentation - follow-up imaging revealed a 1-cm recurrence of the VS and a separate 2.2-cm tumor in the inferior cerebellar parenchyma with surrounding edema. Both tumors were removed without complication by reopening the previous retrosigmoid craniotomy. Histological evaluation of these tumors revealed features typical of VS and similar to those of the tissue obtained from the two prior resections. Given the similarities among these tumors in pathological appearance and mitotic index, the presence of the intraparenchymal cerebellar schwannoma was probably due to intraoperative iatrogenic implantation.

Original languageEnglish (US)
Pages (from-to)452-456
Number of pages5
JournalJournal of neurosurgery
Issue number3
StatePublished - Mar 2006


  • Iatrogenic implantation
  • Surgical implantation
  • Tumor recurrence
  • Tumor seeding
  • Vestibular schwannoma

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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