Hypotension harry: Fatal Forty DDI: Nicardipine, clarithromycin, CYP3A4

Matthew Hart, Bryan J. Read, Wayne T. Nicholson, Toby N. Weingarten

Research output: Chapter in Book/Report/Conference proceedingChapter


This case discusses a pharmacokinetic interaction between nifedipine and clarithromycin resulting in hypotension. Nifedipine is a cytochrome P450 3A4 substrate and clarithromycin is a 3A4 inhibitor.

Original languageEnglish (US)
Title of host publicationA Case Approach to Perioperative Drug-Drug Interactions
PublisherSpringer New York
Number of pages3
ISBN (Electronic)9781461474951
ISBN (Print)9781461474944
StatePublished - Sep 15 2015

ASJC Scopus subject areas

  • General Medicine


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