Home enteral nutrition: A descriptive study

Manpreet S. Mundi, Osman Mohamed Elfadil, Danelle A. Olson, Adele K. Pattinson, Lisa M. Epp, Lisa D. Miller, Sara L. Seegmiller, Jill M. Schneckloth, Margaret R. Baker, Marwa G. Abdelmagid, Ankitaben Patel, Bethaney A. Wescott, Lindsey S. Elder, Martha C. Hagenbrock, Lindsey E. Sefried, Ryan T. Hurt

Research output: Contribution to journalArticlepeer-review


Background: With data demonstrating benefit, the prevalence of home enteral nutrition (HEN) has increased significantly over the last few decades. Despite this increase, there remains a paucity of data regarding real-world use of HEN including clinical outcomes and complications. Methods: Descriptive analysis of prospectively maintained database of our specialized HEN program was undertaken. Patients who received care in our program with HEN initiation date between January 1, 2018, and December 31, 2020, were included in the analysis. Data regarding demographic information, anthropometrics, enteral nutrition (EN) regimen, electrolytes, and nutrition therapy history were included and tracked until July 31, 2021. Results: During the study period, 1600 patients initiated HEN treatment under our care. Majority of the study population needed EN therapy due to malignancy and its complications, including malignant dysphagia or mechanical obstruction (60.6%) followed by neurodegenerative diseases (7.5%). By the end of the study period, a majority of the patients (82%) stopped HEN treatment. Of these, 44.2% achieved EN goals and/or oral autonomy. Patients continued HEN treatment for a median of 100 (interquartile range, 32–301) days. Overall, 53.2% of patients experienced/reported at least one HEN-related complication that was clinically managed by the HEN team. Complications included tube-related, enteral feeding intolerance (EFI), and electrolyte shifts. Conclusion: In our study population, HEN was most utilized to manage malignancy-related complications, including dysphagia. Unfortunately, complications, including EFI and tube-related complications, remained quite prevalent. Further evaluation regarding risk factors for complications and preventive mechanisms, such as increased education, is indicated.

Original languageEnglish (US)
Pages (from-to)550-562
Number of pages13
JournalJournal of Parenteral and Enteral Nutrition
Issue number4
StatePublished - May 2023


  • enteral access
  • enteral feeding intolerance
  • enteral formulas
  • home enteral nutrition

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics


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