High-resolution CT: Can it obviate lung biopsy?

James F. Gruden, David P. Naidich

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The increasing use of high-resolution CT (HRCT) should lead to a reconsideration of the traditional manner in which patients with diffuse interstitial lung disease are evaluated. HRCT is no longer used only in the assessment of rare diseases or exclusively in academic medical centers. There are many clinically important uses of HRCT in patients with pulmonary symptoms; in some cases, the imaging findings are diagnostic and obviate tissue diagnosis. The frequency with which this occurs depends on the type and stage of disease present and on the skill and confidence of the individual interpreting the images Accurate HRCT interpretation also requires correlation with clinical information. The diagnostic evaluation of patients with known or suspected lung disease should involve pulmonologists, thoracic radiologists, and thoracic surgeons.

Original languageEnglish (US)
Pages (from-to)23-35
Number of pages13
JournalClinical Pulmonary Medicine
Issue number1
StatePublished - Jan 1998


  • Bronchoscopy
  • High-resolution CT (HRCT)
  • Interstitial lung disease
  • Lung (biopsy)
  • Lung (computed tomography)
  • Lung disease (diagnosis)

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine


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