Hb Silver Springs [β131(H9)Gln→His], a new hemoglobin variant found in six African-Americans

J. D. Hoyer, M. J. Wick, S. N. Thibodeau, K. S. Kechteiger, J. D. Cook, V. F. Fairbanks

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


We report a new hemoglobin variant which we have named Hb Silver Springs. This variant results from a substitution CAG→CAC (Gln→His) at codon 131 of the β chain. It was detected only by cation exchange high performance liquid chromatography. This is the fifth reported substitution at codon 131. This variant does not appear to have any clinical or hematologic manifestations.

Original languageEnglish (US)
Pages (from-to)37-44
Number of pages8
Issue number1
StatePublished - 1998

ASJC Scopus subject areas

  • Hematology
  • Clinical Biochemistry
  • Genetics(clinical)
  • Biochemistry, medical


Dive into the research topics of 'Hb Silver Springs [β131(H9)Gln→His], a new hemoglobin variant found in six African-Americans'. Together they form a unique fingerprint.

Cite this