GENEHUNTER: Application to analysis of bipolar pedigrees and some extensions

Hongzhe Li, Daniel J. Schaid

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


A newly developed nonparametric multipoint linkage analysis (NPL) by Kruglyak et al. [1996] was applied to the data set from the Johns Hopkins Bipolar Study available through the GAW10 workshop. Our results from GENEHUNTER do not support the analyses of Stine et al. [1995]. Some possible extensions to incorporate unaffecteds are also discussed.

Original languageEnglish (US)
Pages (from-to)659-663
Number of pages5
JournalGenetic epidemiology
Issue number6
StatePublished - 1997


  • Bipolar disease
  • Multipoint linkage analysis

ASJC Scopus subject areas

  • Epidemiology
  • Genetics(clinical)


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