Future Developments in Nonsurgical Epicardial Therapies

Christopher M. Stanton, Samuel J. Asirvatham, Charles J. Bruce, Andrew Danielsen, Paul A. Friedman

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


The unique anatomic position of the pericardium in juxtaposition to central cardiac structures enables it to serve as the ideal vantage point for the delivery of novel cardiovascular therapies. Development of new tools to permit delivery of therapy in the closed pericardial space holds promise for near-surgical access to the heart, without open surgical morbidity. Early observations raise hope for the availability of epicardial leads to enhance cardiac resynchronization therapy designed for subxiphoid nonsurgical percutaneous delivery. Emerging technologies for left atrial appendage ligation may offer new strategies for preventing stroke.

Original languageEnglish (US)
Pages (from-to)135-146
Number of pages12
JournalCardiac Electrophysiology Clinics
Issue number1
StatePublished - Mar 2010


  • Cardiac resynchronization
  • Left atrial appendage
  • Ligation
  • Pericardial space

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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