Frequency compounding in multifrequency vibro-acoustography

Matthew W. Urban, Azra Alizada, Mostafa Fatemia

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations


Vibro-acoustography is a speckle-free ultrasound based imaging modality that can visualize normal and abnormal soft tissue through mapping stimulated acoustic emission. The acoustic emission is generated by focusing two ultrasound beams of slightly different frequencies (Äf = f1-f2) to the same spatial location and vibrating the tissue as a result of ultrasound radiation force. Reverberation of the acoustic emission can create dark and bright areas in the image that affect overall image contrast and detectability of abnormal tissue. Using finite length tonebursts yields acoustic emission at Äf and at sidebands centered about Äf that originate from the temporal toneburst gating. Separate images are formed by bandpass filtering the acoustic emission at Äf and the associated sidebands. The data at these multiple frequencies are compounded through coherent or incoherent processes to reduce the artifacts associated with reverberation of the acoustic emission. Experimental results from a urethane breast phantom and in vivo human breast scans are shown. The reduction in reverberation artifacts are analyzed using a smoothness metric which uses the variances of the gray levels of the original images and those formed through coherent and incoherent compounding of image data. This smoothness metric is minimized when the overall image background is smooth while image features are still preserved. The smoothness metric indicates that the images improved by factors from 1.23-4.33 and 1.09-2.68 in phantom and in vivo studies, respectively. The coherent and incoherent compounding of multifrequency data demonstrate, both qualitatively and quantitatively, the efficacy of this method for reduction of reverberation artifacts.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2009
Subtitle of host publicationUltrasonic Imaging and Signal Processing
StatePublished - 2009
EventMedical Imaging 2009: Ultrasonic Imaging and Signal Processing - Lake Buena Vista, FL, United States
Duration: Feb 8 2009Feb 9 2009

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


OtherMedical Imaging 2009: Ultrasonic Imaging and Signal Processing
Country/TerritoryUnited States
CityLake Buena Vista, FL


  • Acoustic emission
  • Frequency compounding
  • Reverberation
  • Ultrasound
  • Vibro-acoustography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging
  • Biomaterials


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