TY - JOUR
T1 - Focal Cerebral Ischemia
T2 - Pathophysiologic Mechanisms and Rationale for Future Avenues of Treatment
AU - MEYER, FREDRIC B.
AU - SUNDT, THORALF M.
AU - YANAGIHARA, TAKEHIKO
AU - ANDERSON, ROBERT E.
PY - 1987
Y1 - 1987
N2 - Although approximately 500,000 patients suffer from a stroke each year in the United States, treatment of these patients to date has consisted primarily of prevention, supportive measures, and rehabilitation. The modification of experimental cerebral infarction by new pharmacologic agents, along with encouraging results from the restoration of blood flow to areas of focal ischemia in both laboratory and clinical trials, suggests that a more aggressive approach might be considered in selected patients with acute stroke.
AB - Although approximately 500,000 patients suffer from a stroke each year in the United States, treatment of these patients to date has consisted primarily of prevention, supportive measures, and rehabilitation. The modification of experimental cerebral infarction by new pharmacologic agents, along with encouraging results from the restoration of blood flow to areas of focal ischemia in both laboratory and clinical trials, suggests that a more aggressive approach might be considered in selected patients with acute stroke.
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U2 - 10.1016/S0025-6196(12)61523-7
DO - 10.1016/S0025-6196(12)61523-7
M3 - Review article
C2 - 3099103
AN - SCOPUS:0023142591
SN - 0025-6196
VL - 62
SP - 35
EP - 55
JO - Mayo Clinic proceedings
JF - Mayo Clinic proceedings
IS - 1
ER -