Exploring human/animal intersections: Converging lines of evidence in comparative models of aging

John Q. Trojanowski, Joan C. Hendricks, Kathryn Jedrziewski, F. Brad Johnson, Kathryn E. Michel, Rebecka S. Hess, Michael P. Cancro, Meg M. Sleeper, Robert Pignolo, Karen L. Teff, Gustavo D. Aguirre, Virginia M.Y. Lee, Dennis F. Lawler, Allan I. Pack, Peter F. Davies

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


At a symposium convened on March 8, 2007 by the Institute on Aging at the University of Pennsylvania, researchers from the University's Schools of Medicine and Veterinary Medicine explored the convergence of aging research emerging from the two schools. Studies in human patients, animal models, and companion animals have revealed different but complementary aspects of the aging process, ranging from fundamental biologic aspects of aging to the treatment of age-related diseases, both experimentally and in clinical practice. Participants concluded that neither animal nor human research alone will provide answers to most questions about the aging process. Instead, an optimal translational research model supports a bidirectional flow of information from animal models to clinical research.

Original languageEnglish (US)
Pages (from-to)1-5
Number of pages5
JournalAlzheimer's and Dementia
Issue number1
StatePublished - Jan 2008


  • Aging related diseases
  • Model systems for aging research
  • Normal aging
  • Organ specific mechanisms of aging in humans and animals

ASJC Scopus subject areas

  • Clinical Neurology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health
  • Cellular and Molecular Neuroscience
  • Health Policy
  • Developmental Neuroscience
  • Epidemiology


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