Evaluating prognosis

Sumeet K. Asrani, Patrick S. Kamath

Research output: Chapter in Book/Report/Conference proceedingChapter


Liver related mortality is the eighth leading cause of death in the United States and is responsible for a significant proportion of premature mortality. Patients with cirrhosis can survive with compensated disease for several years or have evidence of decompensation, manifested by complications of portal hypertension. Prognosis depends of the clinical stage of disease, underlying disease process, clinical setting, and comorbidities. The Child-Pugh score, model for end-stage liver disease (MELD) score and its derivations, and the hepatic venous pressure gradient are helpful tools to assess prognosis. Disease-specific models are also helpful. Models that incorporate severity of multiple organ dysfunctions are helpful for patients in the intensive care unit or those with acute-on-chronic liver failure.

Original languageEnglish (US)
Title of host publicationCirrhosis
Subtitle of host publicationA Practical Guide to Management
Number of pages12
ISBN (Electronic)9781118412640
ISBN (Print)9781118274828
StatePublished - Jan 30 2015


  • Acute-on-chronic liver failure
  • MELD
  • Prognosis
  • SOFA
  • Survival
  • Variceal bleed
  • Waitlist mortality

ASJC Scopus subject areas

  • General Medicine


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