Epidemiology of Celiac Sprue: A Community‐based Study

Nicholas J. Talley, Miguel Valdovinos, Tanya M. Petterson, Herschel A. Carpenter, L. Joseph Melton

Research output: Contribution to journalArticlepeer-review

101 Scopus citations


Objective: To address the frequency and outcome of celiac disease in a United States community. Methods: We identified all Olmsted County, Minnesota, residents diagnosed with this condition during the period, 1960 through 1990, using the resources of the Rochester Epidemiology Project. Twenty‐eight incident cases (19 women, nine men) were identified. Results: The overall age‐ and gender‐adjusted incidence of celiac disease in the community was 1.2 per 100,000 person‐yr (95% CI 0.7,1.6). There were no significant changes in incidence over time, although rates did increase; the incidence was similar in men and women and rose with age in both genders (p < 0.05). Survival in this inception cohort was 100% at 6 months and 96% at 5 yr, which was not significantly different from expected. The estimated prevalence on January 1, 1991, was 21.8 per 100,000. Conclusion: This study provides the first epi‐demiologic data on celiac disease in the United States.

Original languageEnglish (US)
Pages (from-to)843-846
Number of pages4
JournalThe American Journal of Gastroenterology
Issue number6
StatePublished - Jun 1994

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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