Endothelium-dependent responses and their potential relevance to the distribution of blood flow during hemorrhagic shock

Virginia M Miller; Paul M. Vanhoutte

doi:10.1016/0300-9572(89)90019-1

Endothelium-dependent responses and their potential relevance to the distribution of blood flow during hemorrhagic shock

Virginia M Miller, Paul M. Vanhoutte

Surgery Research

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The endothelium releases vasoactive substances in response to several circulating hormones and to changes in shear stress of the flowing blood across the endothelial surface. Because the distribution of receptors mediating the release of endothelium-derived factors is not uniform along the vascular bed, the vascular endothelium has a potential role in regulating regional blood flow and maintaining peripheral resistance during the course and recovery from hemorrhagic shock.

Original language	English (US)
Pages (from-to)	165-171
Number of pages	7
Journal	Resuscitation
Volume	18
Issue number	2-3
DOIs	https://doi.org/10.1016/0300-9572(89)90019-1
State	Published - 1989

Keywords

Acetylcholine
Adrenoceptors
Arginine vasopressin
Endothelin
Endothelium-derived contracting factor and relaxing factor
Nitric oxide
Renin

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Nursing(all)

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10.1016/0300-9572(89)90019-1

Cite this

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abstract = "The endothelium releases vasoactive substances in response to several circulating hormones and to changes in shear stress of the flowing blood across the endothelial surface. Because the distribution of receptors mediating the release of endothelium-derived factors is not uniform along the vascular bed, the vascular endothelium has a potential role in regulating regional blood flow and maintaining peripheral resistance during the course and recovery from hemorrhagic shock.",

keywords = "Acetylcholine, Adrenoceptors, Arginine vasopressin, Endothelin, Endothelium-derived contracting factor and relaxing factor, Nitric oxide, Renin",

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T1 - Endothelium-dependent responses and their potential relevance to the distribution of blood flow during hemorrhagic shock

AU - Miller, Virginia M

AU - Vanhoutte, Paul M.

PY - 1989

Y1 - 1989

N2 - The endothelium releases vasoactive substances in response to several circulating hormones and to changes in shear stress of the flowing blood across the endothelial surface. Because the distribution of receptors mediating the release of endothelium-derived factors is not uniform along the vascular bed, the vascular endothelium has a potential role in regulating regional blood flow and maintaining peripheral resistance during the course and recovery from hemorrhagic shock.

AB - The endothelium releases vasoactive substances in response to several circulating hormones and to changes in shear stress of the flowing blood across the endothelial surface. Because the distribution of receptors mediating the release of endothelium-derived factors is not uniform along the vascular bed, the vascular endothelium has a potential role in regulating regional blood flow and maintaining peripheral resistance during the course and recovery from hemorrhagic shock.

KW - Acetylcholine

KW - Adrenoceptors

KW - Arginine vasopressin

KW - Endothelin

KW - Endothelium-derived contracting factor and relaxing factor

KW - Nitric oxide

KW - Renin

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AN - SCOPUS:0024374194

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VL - 18

SP - 165

EP - 171

JO - Resuscitation

JF - Resuscitation

IS - 2-3

ER -

Endothelium-dependent responses and their potential relevance to the distribution of blood flow during hemorrhagic shock

Abstract

Keywords

ASJC Scopus subject areas

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